Do you know papova virus ? The first animal vector was devised from the primate named papova virus and siman Virus 40 as we know ( SV40); this virus user in 1979 for cloning. But according to time virus are subsequently developed into many other viruses for example 1-Papilloma virus 2-Adenovirus ( this virus have so many derivatives) 3-The Epstein Barr herpes virus ( derived from herpes virus) 4-Vaccinia virus (used for all mammals) 5- Baculoviruses (for inserts) During 1990s mammalian artificial chromosomes as this name as (MACs) and human artificial chromosomes we can say (HACs) have been developed for human wellfare SV40 vectors As we know this vector have several uses as vectors. It is found in spherical shape with circular and double - stranded 5,243 base pair chromosome. Which coded with 5 proteins as Small-T, large-T , VP1 , VP2 and VP3 Small-T large-T are both early proteins and these VP(1,2,3) are virions protein. These has an origin of rep...
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